A TRANSIENT CORTICAL STATE WITH SLEEP-LIKE SENSORY RESPONSES PRECEDES EMERGENCE FROM GENERAL ANESTHESIA IN HUMANS

A transient cortical state with sleep-like sensory responses precedes emergence from general anesthesia in humans

During awake consciousness, the brain intrinsically maintains a dynamical state in which it can coordinate complex responses to sensory input.How the brain reaches this state spontaneously is not known.General anesthesia provides a unique opportunity to examine how the human brain recovers its functional capabilities after profound unconsciousness.

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Effect of doxycycline in patients of moderate to severe chronic obstructive pulmonary disease with stable symptoms

Background: The protease-antiprotease hypothesis proposes that inflammatory cells and oxidative stress in chronic obstructive pulmonary disease (COPD) produce increased levels of proteolytic enzymes (neutrophil elastase, matrix metalloproteinases [MMP]) which contribute to destruction of parenchyma resulting in progressive decline in forced expirat

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